Recent Projects Utilizing Data from the Psy-ShareD Repository
This project aims to externally validate supervised and unsupervised approaches for identifying treatment resistance.
To assess psychosis as a multisystem disorder of accelerated aging, driven by inflammation and cellular stress.
Accumulating and converging evidence suggests that hippocampal subfield neuropathology might be an important factor underlying psychosis risk, disease progression, and symptomology.
This project will explore whether specific structural brain patterns associated with childhood trauma are linked to distinct cognitive mechanisms—such as source monitoring deficits or intrusive memories—that could contribute to hallucinations in individuals with and without a history of trauma.
The ENIGMA consortium has identified brain structure abnormalities in individuals with Clinical High Risk for Psychosis (CHR) and Schizophrenia (SCZ) using FreeSurfer. However, its parcellation-based method may overlook subtle, widespread differences. This study uses voxel-based morphometry (VBM) to complement ENIGMA’s findings by detecting changes FreeSurfer may miss.
