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Psy-ShareD

Psychosis MRI Shared Data Resource

Combining international pre-existing MRI T1 datasets with linked clinical and cognitive data, into one free-to-access resource.

Publications

New Collaboration

Psy-ShareD is pleased to announce the addition of several prestigious ...

Latest Project

Childhood trauma, hallucinations and brain structural alterations

New Publication Release

MRI data sharing in psychosis: Key challenges and a new Open Access resource ....

Brief Overview & Principles

Psy-ShareD is a new anatomical MRI data sharing initiative that combines high quality, valuable, underutilised pre-existing 'legacy' MRI T1 datasets, with linked clinical and cognitive data into one free-to-access resource.

Currently the Psy-ShareD database hosts pre-existing structural MRI data collected at different sites across Europe, North and Central America, Asia and Australia that are suitable for region of interest, voxel-based morphometry, cortical thickness and surface area analytical approaches.

The following academic institutes are currently part of the project: King's College London, University of Cambridge, University of Oxford, University of Surrey, Brunel University London, University of Birmingham, University of Edinburgh, University of Toyama (Japan), National Institute of Mental Health and Neuro Sciences (India), University of Napels Federico II (Italy), University of Lübeck (Germany), University of Napels Federico II (Italy), University of Napels Federico II (Italy), University of Napels Federico II (Italy), University of Napels Federico II (Italy), University of Napels Federico II (Italy). The database is expected to be live by the end of 2024.

The Psy-ShareD database is accessible to all UK and international academic institutions. This will allow researchers who are not affiliated with the large biomedical schools to be able to conduct well powered research and derive new knowledge about the neuroanatomy of schizophrenia and psychosis.

All datasets contained within the Psy-ShareD database are covered for use by UK National Health Service Database ethical approval. Data access is via a short data access request procedure which is reviewed by the Psy-ShareD Data Management Committee. We are particularly keen to see data access requests from early career researchers.

The database will encompass data from Healthy Controls, as well as from individuals with Psychosis and Psychosis Risk phenotypes i.e.

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Schizophrenia
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First episode psychosis
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Clinical high risk for psychosis
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Familial high risk for psychosis
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High levels of schizotypy
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Bipolar disorder
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Experience of childhood trauma

Our Aims

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To maximise the visibility of the database to ensure global usage
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Develop and use state-of-the-art methods to harmonise and standardise structural MRI, clinical and cognitive data
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Seek out and integrate new MRI datasets, especially those acquired in psychosis and psychosis risk populations from the global South
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Manage the database to ensure its long-term sustainability

The Psy-ShareD project is an international collaboration funded by Medical Research Council that aims to advance understanding of psychosis through shared neuroimaging data .

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Psy-ShareD

Psychosis MRI Shared Data Resource

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Brief Overview & Principles

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